Duplicating objects by dragging with the OPTION key pressed is very common and the same goes for moving objects straight (vertically or horizontally) with the SHIFT key pressed.
I used to combine this two shortcuts to duplicate objects while keeping the new copy aligned to the previous one (by pressing OPTION + SHIFT while dragging).
For some reason, this feature stopped working when I upgraded to ChemDraw 16. Could you help to fix this bug?